WebFeb 25, 2024 · According to the researchers, the riboflavin tetraacetate promotes the oxidation of the carboxylic acid after activation with visible light, followed by a rapid decarboxylation of the generated acyloxyl radical, and trapping of the remaining alkyl radical with TSCN. The reaction tolerates a variety of functional groups.

Cu-catalyzed enantioselective decarboxylative cyanation via …

WebAbstract: An operationally simple method is disclosed for the decarboxylative cyanation of aliphatic carboxylic acids at room temperature. Riboflavin tetraacetate, which is an … WebOct 22, 2024 · A simple and novel methodology for the synthesis of vinyl thiocyanates from decarboxylative cross-coupling reaction of cinnamic acids with KSCN under the s … huntington seven theater huntington indiana

Decarboxylative Cyanation of Aliphatic Carboxylic Acids …

WebThe present review gives an overview over the synthesis of organic nitriles and azides through the decarboxylative cyanation and azidation of carboxylic acids, respectively. Mechanistic features of the reactions are considered and discussed in detail. Webdecarboxylative cyanation of aliphatic carboxylic acids, avoiding the use of stoichiometric bases.[16] Thus, we decided to extend the application of this economic, user-friendly and sustainable protocol to generate alkyl radicals (Scheme 1b) and explore other organic transformations. It is known that nucleophilic alkyl radicals WebABSTRACT An operationally simple method is disclosed for the decarboxylative cyanation of aliphatic carboxylic acids at room temperature. Riboflavin tetraacetate, which is an inexpensive organic photocatalyst, promotes the oxidation of … huntington seven movie theater huntington in